10 Best B Vitamins For Mthfr

Are you on the quest for the ultimate best b vitamins for mthfr? Our dedicated team has invested significant time and resources into exploring the vast market to bring you the cream of the crop in this category. We’ve handpicked and rigorously put a selection of leading best b vitamins for mthfr products through their paces, both in everyday scenarios and in precise, controlled environments. This in-depth testing process helps us to pinpoint both the high points and potential drawbacks of each contender.

Diving into the heart of every best b vitamins for mthfr product, our comprehensive evaluations delve into the vital characteristics of each option. We examine their standout features, overall functionality, and cost-effectiveness, aiming to provide you with a transparent and objective view. We pay close attention to pivotal aspects such as Quality, User-Friendliness, and Affordability. Recognizing the diversity in consumer needs and financial limits, our reviews are crafted to assist you in discovering the best b vitamins for mthfr that aligns perfectly with both your desires and budget.

Editor’s Note: This review has been updated as of March 2024 to include the latest and most relevant information. We have expanded our list to include a broader range of choices, ensuring that our guidance stays up-to-date and versatile, aiding you in navigating through the dynamic landscape of today’s market.

Top Products for best b vitamins for mthfr

# Image Product Name Price
1 Codeage Methylfolate B Complex Supplements - 5 MTHF, Methylcobalamin 1000mcg Methylated Vitamin B12, Riboflavin, Betaine, Vitamins B6, Methylation Cycle MTHFR - 2 Months - 120 Capsules Codeage Methylfolate B Complex Supplements – 5 MTHF, Methylcobalamin 1000mcg Methylated Vitamin B12, Riboflavin, Betaine, Vitamins B6, Methylation Cycle MTHFR – 2 Months – 120 Capsules Buy Now – $35.99 ($0.30 / Count)
2 Vitamin B Complex - 60 Capsules with Vitamins B6 20mg D3 1000IU Magnesium Bisglycinate 260mg Methyl B12 1000mcg and Folate as Methylfolate 600mcg DFE. Doctor Formulated MTHFR Support Supplement. Vitamin B Complex – 60 Capsules with Vitamins B6 20mg D3 1000IU Magnesium Bisglycinate 260mg Methyl B12 1000mcg and Folate as Methylfolate 600mcg DFE. Doctor Formulated MTHFR Support Supplement. Buy Now – $19.97 ($0.33 / Count)
3 Super B-Complex – Methylated Sustained Release Clean Label B Complex with Methylfolate, Boosted B12 Methylcobalamin, Vegan, Lab Verified, 60 Small Tablets, by Igennus Super B-Complex – Methylated Sustained Release Clean Label B Complex with Methylfolate, Boosted B12 Methylcobalamin, Vegan, Lab Verified, 60 Small Tablets, by Igennus Buy Now – $11.19 ($0.19 / Count)
4 Seeking Health B-Minus, Vitamin B Complex to Support Methylation, MTHFR Support, Methyl-Free, Niacin, Biotin Supplement for Women, Vegetarian Capsules (100 Capsules)* Seeking Health B-Minus, Vitamin B Complex to Support Methylation, MTHFR Support, Methyl-Free, Niacin, Biotin Supplement for Women, Vegetarian Capsules (100 Capsules)* Buy Now – $29.95 ($0.30 / Count)
5 Methyl B Complete - 60 Vegetable Capsules | Optimal Methylation Support Supplement with Quatrefolic 5-MTHF (Active folate), Methylcobalamin (Active B12), B2, B6, and TMG | Pharmaceutical Grade Methyl B Complete – 60 Vegetable Capsules | Optimal Methylation Support Supplement with Quatrefolic 5-MTHF (Active folate), Methylcobalamin (Active B12), B2, B6, and TMG | Pharmaceutical Grade Buy Now – $29.97 ($0.50 / Count)
6 Double Strength & Most Bioactive Methyl Folate! Uniquely Formulated with Highest Pharmaceutical Grade Methylcobalamin (B12), Niacin, B1, B2 B6. Works Synergistically for Max Results-3 Month Supply Double Strength & Most Bioactive Methyl Folate! Uniquely Formulated with Highest Pharmaceutical Grade Methylcobalamin (B12), Niacin, B1, B2 B6. Works Synergistically for Max Results-3 Month Supply Buy Now – $22.99 ($0.26 / Count)
7 Seeking Health B Complex Plus, Vitamin B12, Riboflavin, Methylfolate, Choline, Methylated Vitamin B Complex for MTHFR Support, Energy Support, Vegetarian Capsules (100 Capsules)* Seeking Health B Complex Plus, Vitamin B12, Riboflavin, Methylfolate, Choline, Methylated Vitamin B Complex for MTHFR Support, Energy Support, Vegetarian Capsules (100 Capsules)* Buy Now – $29.95 ($0.30 / Count)
8 Pure Encapsulations B-Complex Plus - B Vitamins Supplement to Support Neurological Health, Cardiovascular Health, Energy Levels & Nervous System Support* - with Vitamin B12 & More - 120 Capsules Pure Encapsulations B-Complex Plus – B Vitamins Supplement to Support Neurological Health, Cardiovascular Health, Energy Levels & Nervous System Support* – with Vitamin B12 & More – 120 Capsules Buy Now – $42.00 ($0.35 / Count)
9 Pure Encapsulations MethylAssist 90 Pure Encapsulations MethylAssist 90’s – B Vitamin Complex – Methylation Support* – Heart Health & Brain Health – Non-GMO & Gluten Free – 90 Capsules Buy Now – $59.60 ($0.66 / Count)
10 Integrative Therapeutics Active B-Complex - Energy Metabolism Support* - B-Complex Vitamin Supplement with 8 B-Vitamins, Vitamin B12, Folate, Choline - 60 Capsules Integrative Therapeutics Active B-Complex – Energy Metabolism Support* – B-Complex Vitamin Supplement with 8 B-Vitamins, Vitamin B12, Folate, Choline – 60 Capsules Buy Now – $18.50 ($0.31 / Count)

1. Codeage Methylfolate B Complex Supplements – 5 MTHF, Methylcobalamin 1000mcg Methylated Vitamin B12, Riboflavin, Betaine, Vitamins B6, Methylation Cycle MTHFR – 2 Months – 120 Capsules

Codeage Methylfolate B Complex Supplements - 5 MTHF, Methylcobalamin 1000mcg Methylated Vitamin B12, Riboflavin, Betaine, Vitamins B6, Methylation Cycle MTHFR - 2 Months - 120 Capsules

Key Features:

  • MTHF supplement: Methylfolate B Complex offers an all-in-one methylation supplement with folate, methylated vitamins, riboflavin, and betaine in an easy to use capsule format.
  • Folate & riboflavin: 1360 mcg of 5- MTHF folate with Quatrefolic 5 methylfolate and glucosamine salt as a folate supplement. This methylation formula also contains 30 mg of Riboflavin 5’- Phosphate as a riboflavin supplement.
  • Betaine: The blend features 600 mg of betaine as trimethylglycine (TMG).
  • Methylated vitamins: Codeage Methylfolate B Complex can provide an active, methylated forms of folate and vitamins B2, B6, B12 (5-MTHF and methylcobalamin B12). The vitamins included in this formula (vitamin B6 and vitamin B12 1000 mcg) are also provided in their phosphorylated forms.*
  • Vegan, gluten free, non-GMO, & made in USA: Codeage Methylfolate B Complex supplement is vegan, and non-GMO. This formula is also gluten, dairy, and soy free. Codeage methylated vitamins capsules are manufactured in the USA in an cGMP certified facility and third party tested. 2 months supply.

Buy Now From Amazon – $35.99 ($0.30 / Count)


2. Vitamin B Complex – 60 Capsules with Vitamins B6 20mg D3 1000IU Magnesium Bisglycinate 260mg Methyl B12 1000mcg and Folate as Methylfolate 600mcg DFE. Doctor Formulated MTHFR Support Supplement.

Vitamin B Complex - 60 Capsules with Vitamins B6 20mg D3 1000IU Magnesium Bisglycinate 260mg Methyl B12 1000mcg and Folate as Methylfolate 600mcg DFE. Doctor Formulated MTHFR Support Supplement.

Key Features:

  • NEURO and BRAIN support with B6 as Pyridoxal-5-Phosphate 20mg, B12 as Methylcobalamin 1000mcg, D3 1000IU, Albion Magnesium Bisglycinate 26mg, Folate 600mcg DFE. Support Stamina, Mood, Energy production.
  • With VITAMIN D3 for Immune support. Vitamin B deficiency is often associated with Vitamin D deficiency. Magnesium regulates vitamin B and D3 absorption.
  • With FOLATE (Metafolin L-5-MTHF), not Folic Acid, for MTHFR gene expression, cognitive function support and best B Vitamins absorption.
  • With ALBION MAGNESIUM bisglycinate, the most bioavailable form of magnesium, which is not ionized in the gut and not causing intestinal distress. Controls Vitamins B and D absorption.
  • FORMULATED for people who feel fatigue or have low energy levels, with Vitamin B and D deficiency, methylation difficulties, MTHFR traits. Made in the USA without Magnesium Stearate, Silicon Dioxide or Titanium Dioxide.

Buy Now From Amazon – $19.97 ($0.33 / Count)


3. Super B-Complex – Methylated Sustained Release Clean Label B Complex with Methylfolate, Boosted B12 Methylcobalamin, Vegan, Lab Verified, 60 Small Tablets, by Igennus

Super B-Complex – Methylated Sustained Release Clean Label B Complex with Methylfolate, Boosted B12 Methylcobalamin, Vegan, Lab Verified, 60 Small Tablets, by Igennus

Key Features:

  • HIGH STRENGTH, SUPER ABSORBABLE B complex vitamins including thiamine (B1), Riboflavin-5-phosphate (B2), Nicotinamide (flush free Niacin – B3), Calcium D-pantothenate (B5) & D-Biotin (B7)
  • METHYLATED VITAMIN FORMS that the body utilises immediately: bioavailable folate as methylfolate & methylcobalamin (Vit B12) – no poorly absorbed cyanocobalamin
  • SUSTAINED RELEASE provides all-day nutrient coverage and twice daily dosing optimises B12 levels
  • INTENSIVE HEALTH SUPPORT for energy metabolism, immune and hormonal function, homocysteine regulation, nutrient metabolism, heart function, neurological health. MTHFR-friendly
  • PURE & CLEAN: vegan, non-GMO, hypoallergenic ingredients, no unpleasant fillers (silicon dioxide, magnesium stearate or titanium dioxide). Lab verified, USA & UK GMP manufactured. Small 9mm tablets

Buy Now From Amazon – $11.19 ($0.19 / Count)


4. Seeking Health B-Minus, Vitamin B Complex to Support Methylation, MTHFR Support, Methyl-Free, Niacin, Biotin Supplement for Women, Vegetarian Capsules (100 Capsules)*

Seeking Health B-Minus, Vitamin B Complex to Support Methylation, MTHFR Support, Methyl-Free, Niacin, Biotin Supplement for Women, Vegetarian Capsules (100 Capsules)*

Key Features:

  • Potent vitamin B complex: Provides bioactive B complex, including vitamin B1 (thiamin), vitamin B2 (riboflavin), vitamin B3 (niacin), vitamin B6 (P-5-P), pantothenic acid, and biotin. It’s free of B12 and folate and is a great biotin supplement for women
  • Multiple health benefits: B Minus contains a comprehensive blend of 6 essential B vitamins to support a healthy metabolism, energy production, hormone balance, detoxification, immune system function, positive mood, and cognitive function. The addition of biotin also supports healthy skin, hair, and nail growth
  • Methylation support: Contains high-quality B complex vitamins, without vitamin B12 or folate; an especially great option for those sensitive to methylated nutrients
  • Free from: Eggs, fish, gluten, GMO, milk, peanuts, shellfish, soy, tree nuts, wheat, artificial colors, artificial flavors, and artificial preservatives
  • Consistent quality: At Seeking Health, every ingredient is carefully sourced, researched, and tested. Each meets strict specifications for manufacturing and quality standards before any ingredient is allowed for use

Buy Now From Amazon – $29.95 ($0.30 / Count)


5. Methyl B Complete – 60 Vegetable Capsules | Optimal Methylation Support Supplement with Quatrefolic 5-MTHF (Active folate), Methylcobalamin (Active B12), B2, B6, and TMG | Pharmaceutical Grade

Methyl B Complete - 60 Vegetable Capsules | Optimal Methylation Support Supplement with Quatrefolic 5-MTHF (Active folate), Methylcobalamin (Active B12), B2, B6, and TMG | Pharmaceutical Grade

Key Features:

  • ADVANCED FORMULA: The ultimate B complex vitamins for women and men alike, our Vitamin B complex provides essential B vitamins to support methylation processes. Featuring Folate as Quatrefolic for increased bioactivity, Betaine (also known as Trimethylglycine or TMG), and Vitamins B12 (Methylcobalamin and Adenosylcobalamin), B6, and B2, ours is a super B complex that provides vitamins essential for overall wellbeing, including energy production.
  • SIMPLY PURE INGREDIENTS: You absolutely won’t find any fillers, excipients, or flow agents in these methyl B complex vegan supplements. Moreover, our Vitamin B supplements contain absolutely no gluten, wheat, soy, corn, yeast, animal products, nuts, artificial preservatives, sweeteners, or colors. We always promise to put quality first with absolutely no exceptions.
  • MANUFACTURED IN THE USA: Manufactured in NSF-certified facilities right here in the USA, our third-party tested B vitamin complex follows the FDA’s strict cGMP guidelines. Each bottle of our B complex vitamin supplement contains sixty (60) capsules. Each capsule contains 25 mg Riboflavin, 15 mg Vitamin B6, 3,400 mcg Folate, 1,000 mcg Vitamin B12, and 650 mg TMG.
  • EASY TO TAKE B-COMPLEX VITAMIN SUPPLEMENTS: These vegan friendly vitamin B complex capsules are easy-to-swallow – Simply take one (1) or two (2) capsules with a meal/food daily or as directed by your qualified healthcare practitioner.
  • ABOUT US: Pure TheraPro Rx was founded in Denver Colorado to formulate and manufacture the highest quality supplements available on the market today. Purity is our priority, which is why we insist on using patented, clinically studied ingredients, and never utilizing fillers, flow agents, excipients, or ingredients sourced from China. We also never use dairy, gluten, corn, soy, or other common allergens in any of our class-leading, practitioner-recommended formulas.

Buy Now From Amazon – $29.97 ($0.50 / Count)


6. Double Strength & Most Bioactive Methyl Folate! Uniquely Formulated with Highest Pharmaceutical Grade Methylcobalamin (B12), Niacin, B1, B2 B6. Works Synergistically for Max Results-3 Month Supply

Double Strength & Most Bioactive Methyl Folate! Uniquely Formulated with Highest Pharmaceutical Grade Methylcobalamin (B12), Niacin, B1, B2 B6. Works Synergistically for Max Results-3 Month Supply

Key Features:

  • ♥ Lab tested and most powerful Methylfolate supplying essential support for DNA and neurotransmitter synthesis along with amino acid metabolism.
  • ♥ Developed as most optimally absorbed and bioavailable 5-MTHF
  • ♥ Delivering key supplementation for brain, heart and nerve function, as well as support for women who are pregnant and overall health
  • ♥ Suitable for people who are diagnosed with MTHFR mutation
  • ♥ To ensure purity and safety, our products are manufactured in a fully GMP-certified facility. Our product is third party tested to assure the quality and purity of each batch. All Made in USA.

Buy Now From Amazon – $22.99 ($0.26 / Count)


7. Seeking Health B Complex Plus, Vitamin B12, Riboflavin, Methylfolate, Choline, Methylated Vitamin B Complex for MTHFR Support, Energy Support, Vegetarian Capsules (100 Capsules)*

Seeking Health B Complex Plus, Vitamin B12, Riboflavin, Methylfolate, Choline, Methylated Vitamin B Complex for MTHFR Support, Energy Support, Vegetarian Capsules (100 Capsules)*

Key Features:

  • Essential B Vitamins: Contains comprehensive blend of 8 essential B vitamins plus choline to support critical enzyme reactions and methylation, and provide MTHFR support. For those sensitive to methylated ingredients, consider our B Complex MF
  • Energy, liver, and brain support: B Complex Plus helps support healthy energy levels via the active forms of B12 (as methylcobalamin), vitamin B2 (riboflavin), and methylated folate (methylfolate or 5-MTHF). Choline may help support liver and brain health, while biotin may help support healthy skin and nails
  • Contains niacin: If you are sensitive to niacin, you may experience a “flush” sensation when using B Complex Plus. Niacin dilates blood vessels and increases circulation under the skin. This can cause redness, itching, tingling or a sensation of warmth- especially in the face, neck, or upper torso. If you believe that you are experiencing any adverse reactions, see your healthcare professional immediately. We always recommend consulting your healthcare professional before using any supplement
  • Free from: Eggs, fish, gluten, GMO, milk, peanuts, shellfish, soy, tree nuts, wheat, artificial colors, artificial flavors, and artificial preservatives
  • Consistent quality: At Seeking Health, every ingredient is carefully sourced, researched, and tested. Each meets strict specifications for manufacturing and quality standards before any ingredient is allowed for use

Buy Now From Amazon – $29.95 ($0.30 / Count)


8. Pure Encapsulations B-Complex Plus – B Vitamins Supplement to Support Neurological Health, Cardiovascular Health, Energy Levels & Nervous System Support* – with Vitamin B12 & More – 120 Capsules

Pure Encapsulations B-Complex Plus - B Vitamins Supplement to Support Neurological Health, Cardiovascular Health, Energy Levels & Nervous System Support* - with Vitamin B12 & More - 120 Capsules

Key Features:

  • Nervous System Support: Supports the nervous and cardiovascular system plus healthy nerve and blood cells; also supports hair, skin and nails*
  • Cognitive Support: Methylated Folate (Metafolin L-5-MTHF) and vitamin B12 support healthy cognitive function, memory, and energy; also supports G.I. tract*
  • Premium Cellular Energy Support for Women and Men: B vitamins support metabolism of protein and conversion of carbohydrates into energy*
  • Supports Cognitive Health: This vitamin B complex supplement supports memory, energy, and metabolism*
  • Pure Difference: What we leave out matters, too; Pure Encapsulations products are free from common allergens, artificial or unnecessary ingredients, and GMOs

Buy Now From Amazon – $42.00 ($0.35 / Count)


9. Pure Encapsulations MethylAssist 90’s – B Vitamin Complex – Methylation Support* – Heart Health & Brain Health – Non-GMO & Gluten Free – 90 Capsules

Pure Encapsulations MethylAssist 90

Key Features:

  • B Vitamin Complex: MethylAssist 90’s features a vitamin B complex including activated B6, B12, and benfotiamine, making it an exceptional vitamin B supplement for neuronal health*
  • Comprehensive Benefits: Supports cardiovascular and neuronal wellness, with the vitamin B complex playing key roles in methylation processes*
  • Methylation Support: Provides essential methylation support with Metafolin L-5-MTHF, an effective methylfolate supplement*
  • Suggested Use: As a dietary supplement, take 1 vitamin B supplement capsule daily, with a meal, or as directed by a health professional
  • Pure Difference: What we leave out matters, too; Pure Encapsulations products are FREE FROM common allergens, artificial or unnecessary ingredients, and GMOs

Buy Now From Amazon – $59.60 ($0.66 / Count)


10. Integrative Therapeutics Active B-Complex – Energy Metabolism Support* – B-Complex Vitamin Supplement with 8 B-Vitamins, Vitamin B12, Folate, Choline – 60 Capsules

Integrative Therapeutics Active B-Complex - Energy Metabolism Support* - B-Complex Vitamin Supplement with 8 B-Vitamins, Vitamin B12, Folate, Choline - 60 Capsules

Key Features:

  • Active B-Complex Supplement: Provides all 8 B-vitamins in a high-potency blend containing active forms of vitamins B2, B6, B12, and folate; includes choline to support healthy brain function*
  • Cellular Energy Production: Supports cellular energy production through the metabolism of carbohydrates, proteins, and lipids; converts food into fuel to help you tackle the day*
  • Essential B Vitamins: B vitamins play essential roles in supporting cell function, the nervous system, and cellular energy production; supports the synthesis of serotonin, dopamine, and GABA*
  • Nervous & Immune System Support: Folate plays an essential role in nervous system and immune system functions*; our supplement is formulated with the Quatrefolic brand L-methylfolate
  • About Integrative Therapeutics: Our supplements are trusted by physicians and backed by science; every product is held to our high standards and rigorously tested

Buy Now From Amazon – $18.50 ($0.31 / Count)


Essential Buyer’s Guide for Selecting the Perfect best b vitamins for mthfr

Identify Your Requirements

Pinpoint what you specifically need from the best b vitamins for mthfr. Understand the features and functionalities that are most critical for your use-case to narrow down your choices.

Inspect Product Quality

Always prioritize the quality of the best b vitamins for mthfr. High-quality items tend to last longer and provide better performance. Look for products with strong materials, good build quality, and positive user feedback.

Assess Brand Reputation

The brand’s history can tell you a lot about the quality and reliability of the best b vitamins for mthfr. A reputable brand usually guarantees a certain level of quality and customer service.

Vendor Credibility

Consider the credibility of the seller or manufacturer. A reputable vendor or manufacturer often correlates with better customer service and product reliability.

User Reviews and Ratings

Take the time to read through user reviews and ratings. They offer valuable insights into how the best b vitamins for mthfr performs in real-world scenarios and can highlight any potential issues.

Longevity and Maintenance

Consider how long the best b vitamins for mthfr lasts under normal use. A product that requires less maintenance and is more durable is typically a better investment.

Usability and Convenience

Ensure the best b vitamins for mthfr is easy to use and fits comfortably into your routine or lifestyle. User-friendly products enhance your experience and are more likely to satisfy your needs.

Compare Price to Value

Evaluate if the best b vitamins for mthfr’s price is reflective of its value. Sometimes paying a little extra upfront can save you money in the long run due to better quality or features.

Product Availability

Check the availability of the best b vitamins for mthfr. Products that are easily accessible tend to have better after-sales support and availability of parts or accessories.

Comprehensive Comparison

Compare different best b vitamins for mthfr products against each other. Look at each option’s features, benefits, and drawbacks to make an informed decision.

Warranty and After-Sales Support

A solid warranty and reliable customer support can greatly enhance your experience with the best b vitamins for mthfr. These factors can also provide peace of mind and save costs in the future.

Stay Updated

The market is always evolving. Keep an eye on new releases and developments to ensure you choose a best b vitamins for mthfr that remains relevant and up to date.

Make Your Final Choice

After thorough consideration, choose the best b vitamins for mthfr that best meets your criteria and expectations, balancing all factors like quality, usability, and cost.

Our reviews and guides are meticulously curated to assist you in navigating the selection process, helping you make a choice that’s both satisfying and well-informed.


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